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aripiprazole (Abilify Maintena / Lu AF41155 / aripiprazole ERIS)

✓ Approved

Otsuka Holdings Co., Ltd. · DRD2 · Small Molecule

What is aripiprazole?

aripiprazole is a small molecule developed by Otsuka Holdings Co., Ltd.. It is approved for therapeutic indications via injectable (others) or intramuscular (im) injection.

Drug Profile

Brand NamesAbilify Maintena, Lu AF41155, aripiprazole ERIS
CompanyOtsuka Holdings Co., Ltd.
Drug ClassSmall Molecule
Molecular TargetDRD2, HTR1A, HTR2A
RouteInjectable (Others), Intramuscular (IM) Injection
StatusApproved
Sources: ClinicalTrials.gov, Otsuka Holdings Co., Ltd.

Mechanism of Action

Molecular Targets

aripiprazole acts on 3 molecular targets:

DRD2dopamine receptor D2 (D2DR, D2R)
HTR1A5-hydroxytryptamine receptor 1A (PFMCD, 5-HT1A)
HTR2A5-hydroxytryptamine receptor 2A (5-HT2A, HTR2)
Want deeper analysis?Noah AI can explain complex mechanisms and compare to similar drugs.

Therapeutic Indications

aripiprazole is developed for 2 unique indications across 1 therapeutic area.

Therapeutic AreaConditionPhase
Psychiatric disordersSchizophrenia✓ Approved
Psychiatric disordersBipolar disorder✓ Approved

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