baclofen Latest Research Articles & Clinical Trials & Targets & Indications

What is baclofen?

baclofen is a small molecule developed by Metacel Pharmaceuticals. It is approved for therapeutic indications via oral (po).

baclofen acts on 1 molecular target:

GABBR1

gamma-aminobutyric acid type B receptor subunit 1 (GABABR1, GB1)

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There are currently 116 clinical trials registered

Trial ID	Phase	Title	Status
NCT04523935	Phase 4	Excessive Crying in Children With Cerebral Palsy and Communication Deficits -a Fixed-sequence, Cross	Completed
NCT03034408	Phase 2	Effects of Nalmefene and Baclofen on Impulsivity in Subjects With Alcohol Use Disorder and Healthy C	Completed
NCT05161351	Phase 4	Evaluating the Safety of Acute Baclofen in Methadone-maintained Individuals With Opiate Dependence.	Unknown
NCT02998151	EARLY_Phase 1	Neurophysiological and Acute Pharmacological Studies in FXS Patients	Completed
NCT01003249	Phase 4	Treatment of Patients With Dysfunctional Voiding and Lower Urinary Tract Symptoms With Baclofen: a R	Terminated
NCT01008280	Phase 4	Efficacy & Safety of Baclofen to Reduce Alcohol Use in Veterans With HCV	Completed

+112 more trials available with a free account

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baclofen is developed for 1 unique indication across 1 therapeutic area.

Therapeutic Area	Condition	Phase
Nervous system disorders	Muscle spasticity	✓ Approved