CLYM116
- Indication
- Immunoglobulin A Nephropathy
- Stage
- phase1
- Event
- Conference Presentation
- Details
October 2, 2026: Climb Bio, Inc. (NASDAQ: CLYM) said it will present new clinical data on CLYM116 and budoprutug at ASN Kidney Week 2026 in Denver (October 21-25, 2026), with abstracts already available on the ASN website.
CLYM116: two ASN poster presentations will report preliminary/Phase 1 healthy-volunteer data on safety, tolerability, pharmacokinetics, and pharmacodynamics for the anti-APRIL monoclonal antibody being developed for IgA nephropathy. Presentations are scheduled for October 22 and October 23, 2026.
Budoprutug: preliminary Phase 2 data from the ongoing PrisMN study in primary membranous nephropathy were selected for an oral presentation on October 24, 2026. A separate poster on October 23, 2026 will present a minimal change disease case study describing durable response and potential disease modification via CD19+ B-cell depletion.
The release does not provide efficacy or numerical study results, but highlights upcoming data presentations across primary membranous nephropathy, minimal change disease, and IgA nephropathy. It also states budoprutug has FDA Orphan Drug and Fast Track designations for primary membranous nephropathy.
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